Our platform

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Beating aggressive cancers with pluripotent stem cell-based immunotherapies

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A novel class of Cancer-Associated stemness targets for Immuno-Oncology

iPSC-based immunotherapy

We are employing innovative Induced Pluripotent Stem Cells (iPSC)-based immunotherapies against aggressive forms of cancers to solve the three major hurdles associated with cancer treatment : treatment resistance, metastatic spread, and relapse.

iPSirius' proprietary IPVAC technology enables patient's immune system to specifically recognize and respond to thousands of antigens found in CSC while converting the tumor microenvironment from a state where the immune system is suppressed to a state where it becomes more active and responsive. This means shifting the conditions within the tumor to make it easier for the immune system to recognize and attack cancer cells. With IPVAC, we aim to enhance the body's natural defense mechanisms and improve the chances of effectively eradicating CSC, the root of cancer.

33 patents across 13 territories granted in USA, Israel, Canada, Australia, Japan, Russia, South Korea

Our pipeline

Our Approach to Treat a Range of Aggressive Cancers :

We are developing active immunotherapies based on Induced Pluripotent Stem Cells (iPSC) that presents a new avenue for treating a variety of late stage cancers with a stemness signature including non-small cell lung cancer, glioblastoma, triple negative breast cancer and pancreatic cancer.   Our products can be administered as single agent or in combination with other therapies to enhance anti-tumor immunity improving prognoses and therapeutic options for patients.

iPVAC : Agnostic Cancer Vaccines

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